Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD1 | P21728 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8905972 | 0.77 | KDM4E (0.59) | CYP3A4MEN1CYP2D6KMT2ADRD2 | |
| Bromide SCHEMBL8904455 | 0.75 | KDM4E (0.56) | CYP3A4MEN1CYP2D6KMT2ADRD2 | |
| SCHEMBL14494799 | 0.72 | PARP1 (0.68) | CYP3A4MEN1CYP2D6KMT2ADRD2 | |
| SCHEMBL11102977 | 0.72 | PARP1 (0.68) | CYP3A4MEN1CYP2D6KMT2ADRD2 | |
| SCHEMBL27520396 | 0.72 | IGF1R (0.38) | CYP3A4CYP2D6DRD2DRD1ALOX15 | |
| SCHEMBL11086909 | 0.71 | DRD1 (0.61) | CYP3A4MEN1CYP2D6KMT2ADRD2 | |
| SCHEMBL8904833 | 0.70 | ACHE (0.44) | CYP3A4MEN1CYP2D6KMT2ADRD1 | |
| SCHEMBL8904748 | 0.70 | HTR2A (0.44) | CYP3A4MEN1CYP2D6KMT2ADRD1 | |
| SCHEMBL18585775 | 0.70 | CYP3A4 (0.66) | CYP3A4MEN1CYP2D6KMT2ADRD2 | |
| SCHEMBL4312910 | 0.70 | CYP2D6 (0.66) | CYP3A4MEN1CYP2D6KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553233-B | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | DECIPHERA PHARMACEUTICALS LLC | 2013-05-29 | — | — | CN | disclosed |
| CN-101553233-A | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-10-07 | — | — | CN | disclosed |