Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27664587 | 1.00 | DPP4 (0.35) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL27684119 | 1.00 | DPP4 (0.35) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL27713182 | 0.83 | HRH2 (0.31) | — | |
| SCHEMBL27733586 | 0.83 | HRH2 (0.31) | — | |
| SCHEMBL27720226 | 0.83 | HRH2 (0.31) | — | |
| SCHEMBL28214294 | 0.82 | DPP4 (0.34) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4698579 | 0.81 | CHRM2 (0.36) | DPP4CTSKRIPK1 | |
| SCHEMBL28265971 | 0.81 | ALDH1A1 (0.33) | DPP4DPP8DPP7CTSKRIPK1 | |
| SCHEMBL4399555 | 0.81 | CHRM2 (0.36) | DPP4CTSKRIPK1 | |
| SCHEMBL28012712 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414435-A | Amino-substituted isothiazoles | 拜耳制药股份公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-105612153-A | Substituted sulfonamide compounds as TRPA1 conditioner | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |
| CN-104447707-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-03-25 | — | — | CN | disclosed |
| CN-101558059-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-12-03 | — | — | CN | disclosed |
| CN-101558059-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | CN | disclosed |