Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437416 | 0.84 | MET (0.60) | METPOLBMAPK1SMN1; SMN2CTNNB1 | |
| SCHEMBL1583361 | 0.80 | MET (0.80) | METPOLBMAPK1SMN1; SMN2RPS6KA3 | |
| SCHEMBL2011081 | 0.80 | MET (0.67) | METPOLBMAPK1SMN1; SMN2RPS6KA3 | |
| SCHEMBL4997410 | 0.79 | MET (0.58) | METPOLBMAPK1SMN1; SMN2CTNNB1 | |
| SCHEMBL1982875 | 0.77 | MET (0.63) | METPOLBMAPK1SMN1; SMN2RPS6KA3 | |
| SCHEMBL4987926 | 0.76 | MET (0.61) | METPOLBMAPK1SMN1; SMN2RPS6KA3 | |
| SCHEMBL2011745 | 0.76 | MET (0.61) | METPOLBMAPK1SMN1; SMN2RPS6KA3 | |
| SCHEMBL2013113 | 0.75 | MET (0.63) | METPOLBMAPK1SMN1; SMN2RPS6KA3 | |
| SCHEMBL4437291 | 0.74 | MET (0.57) | METPOLBMAPK1SMN1; SMN2RPS6KA3 | |
| SCHEMBL2009516 | 0.74 | MET (0.67) | METPOLBMAPK1SMN1; SMN2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101558040-A | Dihydropyridine derivatives useful as protein kinase inhibitors | BAYER SCHERING PHARMA AG (DE) | 2009-10-14 | — | — | CN | claimed |
| CN-101558040-A | Dihydropyridine derivatives useful as protein kinase inhibitors | BAYER SCHERING PHARMA AG (DE) | 2009-10-14 | — | — | CN | disclosed |