Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 9/20 | 0.59 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384172 | 0.97 | LTA4H (0.62) | LTA4HBACE1BACE2CTSDMME | |
| SCHEMBL30903468 | 0.95 | LTA4H (0.63) | LTA4HBACE1BACE2CTSDMME | |
| SCHEMBL31720977 | 0.95 | LTA4H (0.63) | LTA4HBACE1BACE2CTSDMME | |
| SCHEMBL29772150 | 0.93 | BACE1 (0.62) | BACE1BACE2CTSD | |
| SCHEMBL29385423 | 0.91 | LTA4H (0.58) | LTA4HBACE1BACE2CTSDMME | |
| SCHEMBL31022699 | 0.91 | BACE1 (0.64) | BACE1BACE2CTSDNAALAD2 | |
| SCHEMBL30745233 | 0.91 | IL1RN (0.59) | BACE1BACE2NAALAD2 | |
| SCHEMBL30804672 | 0.91 | BACE1 (0.69) | BACE1BACE2CTSDNAALAD2 | |
| SCHEMBL32667937 | 0.91 | BACE1 (0.66) | LTA4HBACE1BACE2CTSDNAALAD2 | |
| SCHEMBL30193491 | 0.91 | NAALAD2 (0.60) | LTA4HBACE1BACE2CTSDNAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101715454-A | Tumor selective and biodegradable cyclotriphosphazene-platinum(II) conjugate anticancer agent, and preparation method thereof | NANOHYBRID CO LTD | 2010-05-26 | — | — | CN | claimed |
| CN-101715454-A | Tumor selective and biodegradable cyclotriphosphazene-platinum(II) conjugate anticancer agent, and preparation method thereof | NANOHYBRID CO LTD | 2010-05-26 | — | — | CN | disclosed |