Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | DPP4 | P27487 | 7/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3840015 | 0.99 | KCNH2 (0.42) | KCNH2DPP4KDM1ADRD2SLC6A4 | |
| SCHEMBL704957 | 0.91 | KCNH2 (0.47) | KCNH2DPP4KDM1ACYP3A4CYP2D6 | |
| SCHEMBL4770655 | 0.85 | KCNH2 (0.41) | KCNH2DPP4DRD2SLC6A4HTR2A | |
| SCHEMBL4302199 | 0.84 | KCNH2 (0.47) | KCNH2DRD2HTR2AHTR2C | |
| SCHEMBL4303624 | 0.80 | HTR2C (0.43) | DRD2SLC6A4HTR2AHTR2C | |
| SCHEMBL4302247 | 0.79 | KCNA3 (0.49) | KCNH2DPP4DRD2 | |
| SCHEMBL705731 | 0.78 | KCNH2 (0.40) | KCNH2DRD2SLC6A4HTR2AHTR2C | |
| SCHEMBL705950 | 0.78 | SCN7A (0.43) | KCNH2KDM1A | |
| SCHEMBL706822 | 0.78 | KCNH2 (0.43) | KCNH2DRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL3870194 | 0.77 | KCNH2 (0.43) | KCNH2DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516889-B | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101516889-A | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | CN | disclosed |