Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780802 | 0.85 | KCNH2 (0.43) | KCNH2DRD2SLC6A4DPP4HTR2A | |
| Hydrochloric Acid SCHEMBL3840015 | 0.84 | KCNH2 (0.42) | KCNH2DRD2SLC6A4DPP4HTR2A | |
| SCHEMBL4302199 | 0.80 | KCNH2 (0.47) | KCNH2DRD2DRD3HTR2AHTR2C | |
| SCHEMBL3838931 | 0.80 | KCNH2 (0.34) | KCNH2DPP4 | |
| SCHEMBL4771515 | 0.77 | ALDH1A1 (0.37) | KCNH2SCN7ADRD2SLC6A4SCN5A | |
| SCHEMBL704957 | 0.76 | KCNH2 (0.47) | KCNH2SCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL4302247 | 0.75 | KCNA3 (0.49) | KCNH2DRD2PLK1DPP4 | |
| SCHEMBL3839711 | 0.74 | KCNH2 (0.66) | KCNH2 | |
| SCHEMBL12047110 | 0.73 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4776915 | 0.72 | KCNH2 (0.47) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |