Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349349 | 0.96 | EPHX2 (0.62) | POLBEPHX2L3MBTL1SMN1; SMN2EPHX1 | |
| SCHEMBL27782813 | 0.83 | SMN1; SMN2 (0.76) | L3MBTL1SMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL27782809 | 0.83 | POLB (0.61) | POLBEPHX2L3MBTL1SMN1; SMN2EPHX1 | |
| SCHEMBL11110593 | 0.81 | POLB (0.81) | POLBEPHX2L3MBTL1SMN1; SMN2EPHX1 | |
| SCHEMBL4127306 | 0.81 | EPHX2 (0.68) | POLBEPHX2L3MBTL1SMN1; SMN2EPHX1 | |
| SCHEMBL13136760 | 0.80 | POLB (0.69) | POLBEPHX2L3MBTL1SMN1; SMN2EPHX1 | |
| SCHEMBL4346935 | 0.80 | ALDH1A1 (0.49) | EPHX2SMN1; SMN2EPHX1HTTALDH1A1 | |
| SCHEMBL4350067 | 0.79 | SMN1; SMN2 (0.70) | EPHX2L3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4351245 | 0.79 | TRPV1 (0.58) | SMN1; SMN2EPHX1MAPT | |
| SCHEMBL4357568 | 0.79 | EPHX1 (0.58) | POLBEPHX2L3MBTL1EPHX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |