Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816200 | 1.00 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL12806778 | 0.90 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL12806751 | 0.89 | SLC6A4 (0.64) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL7094571 | 0.88 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL14035499 | 0.86 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL5139722 | 0.86 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL5074166 | 0.84 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL8907832 | 0.84 | SLC6A2 (0.56) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL10413788 | 0.83 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL5444533 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101512336-A | Stimulation of pancreatic beta cell proliferation | UNIV ROCKEFELLER (US) | 2009-08-19 | — | — | CN | claimed |
| CN-101512336-A | Stimulation of pancreatic beta cell proliferation | UNIV ROCKEFELLER (US) | 2009-08-19 | — | — | CN | disclosed |