Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722465 | 0.90 | ADRA2A (0.50) | SLC6A4MC4R | |
| SCHEMBL9816200 | 0.88 | SLC6A4 (0.69) | SLC6A4CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL27782829 | 0.88 | SLC6A4 (0.69) | SLC6A4CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL9284849 | 0.81 | ADRA2A (0.46) | MC4R | |
| SCHEMBL30269771 | 0.80 | GBA1 (0.42) | SLC6A4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL12508381 | 0.78 | KCNA5 (0.48) | SLC6A4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL12806778 | 0.78 | SLC6A4 (0.66) | SLC6A4CYP1A2CYP2C19CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9850163 | 0.77 | OPRL1 (0.38) | SLC6A4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL12806751 | 0.77 | SLC6A4 (0.64) | SLC6A4CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3583059 | 0.76 | OPRL1 (0.63) | SLC6A4OPRL1CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089476-A1 | CROSS-LINKED HYALURONATE COMPOUNDS | GENZYME CORPORATION (US) | 2003-10-30 | — | — | WO | claimed |
| WO-2003089476-A1 | CROSS-LINKED HYALURONATE COMPOUNDS | GENZYME CORPORATION (US) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003089026-A1 | AZIRIDINE COMPOUNDS AND THEIR USE IN MEDICAL DEVICES | GENZYME CORPORATION (US) | 2003-10-30 | — | — | WO | disclosed |