Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | PDE5A | O76074 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PDE1A | P54750 | 1/20 | 0.55 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.55 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.55 |
| ▸ | SCD | O00767 | 3/20 | 0.55 |
| ▸ | KDM4A | O75164 | 1/20 | 0.54 |
| ▸ | KDM4B | O94953 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874993 | 0.91 | AOC3 (0.74) | AOC3KDM4EPDE5ANPC1RAB9A | |
| SCHEMBL13679462 | 0.86 | AOC3 (0.70) | AOC3KDM4EPDE5ANPC1RAB9A | |
| SCHEMBL4874675 | 0.85 | AOC3 (0.63) | AOC3KDM4EPDE5ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4875657 | 0.85 | AOC3 (0.71) | AOC3KDM4EPDE5ANPC1RAB9A | |
| SCHEMBL8430108 | 0.84 | AOC3 (0.76) | AOC3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL91391 | 0.83 | KDM4E (0.69) | AOC3KDM4EPDE5ANPC1RAB9A | |
| SCHEMBL27599948 | 0.83 | KDM4E (0.78) | AOC3KDM4EPDE5ANPC1RAB9A | |
| SCHEMBL2227204 | 0.83 | KDM4E (0.69) | AOC3KDM4EPDE5ANPC1RAB9A | |
| SCHEMBL2664517 | 0.83 | KDM4E (0.69) | AOC3KDM4EPDE5ANPC1RAB9A | |
| Carbamic Acid SCHEMBL4874681 | 0.82 | AOC3 (0.67) | AOC3KDM4EPDE5ASCDCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747327-A | Aromatic amide thiazole derivative, preparation method and application thereof | UNIV BEIJING | 2010-06-23 | — | — | CN | claimed |
| CN-101747327-B | Aromatic amide thiazole derivative, preparation method and application thereof | UNIV BEIJING | 2013-03-27 | — | — | CN | disclosed |
| CN-101747327-A | Aromatic amide thiazole derivative, preparation method and application thereof | UNIV BEIJING | 2010-06-23 | — | — | CN | disclosed |