Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 1.00 |
| ▸ | BCR | P11274 | 13/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.78 |
| ▸ | KIT | P10721 | 4/20 | 0.78 |
| ▸ | LCK | P06239 | 3/20 | 0.78 |
| ▸ | LYN | P07948 | 3/20 | 0.78 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.78 |
| ▸ | FLT3 | P36888 | 3/20 | 0.78 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.78 |
| ▸ | LDLR | P01130 | 2/20 | 0.78 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.78 |
| ▸ | HCK | P08631 | 2/20 | 0.78 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.78 |
| ▸ | CA12 | O43570 | 1/20 | 0.78 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.78 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.78 |
| ▸ | STK10 | O94804 | 1/20 | 0.78 |
| ▸ | CA1 | P00915 | 1/20 | 0.78 |
| ▸ | CA2 | P00918 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804465 | 0.94 | ABL1 (1.00) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27804457 | 0.91 | ABL1 (0.86) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27782902 | 0.91 | ABL1 (1.00) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27782897 | 0.90 | ABL1 (1.00) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27804459 | 0.90 | ABL1 (1.00) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27782911 | 0.89 | ABL1 (0.86) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27804464 | 0.89 | ABL1 (0.85) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL5023657 | 0.88 | ABL1 (0.80) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27782899 | 0.88 | ABL1 (1.00) | ABL1BCRPDGFRBKITLCK | |
| SCHEMBL27782893 | 0.88 | ABL1 (0.79) | ABL1BCRPDGFRBKITLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747330-B | Pyridyl thiazole amine compound and medicinal composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2012-03-21 | — | — | CN | disclosed |
| CN-101747330-A | Pyridyl thiazole amine compound and medicinal composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2010-06-23 | — | — | CN | disclosed |