Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 19/20 | 1.00 |
| ▸ | BCR | P11274 | 14/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.63 |
| ▸ | KIT | P10721 | 3/20 | 0.63 |
| ▸ | BRAF | P15056 | 3/20 | 0.63 |
| ▸ | LCK | P06239 | 2/20 | 0.63 |
| ▸ | FYN | P06241 | 2/20 | 0.63 |
| ▸ | CSF1R | P07333 | 2/20 | 0.63 |
| ▸ | YES1 | P07947 | 2/20 | 0.63 |
| ▸ | LYN | P07948 | 2/20 | 0.63 |
| ▸ | HCK | P08631 | 2/20 | 0.63 |
| ▸ | FGR | P09769 | 2/20 | 0.63 |
| ▸ | SRC | P12931 | 2/20 | 0.63 |
| ▸ | NQO2 | P16083 | 2/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.63 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.63 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.63 |
| ▸ | ABL2 | P42684 | 2/20 | 0.63 |
| ▸ | FRK | P42685 | 2/20 | 0.63 |
| ▸ | BLK | P51451 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782901 | 0.94 | ABL1 (0.88) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27804477 | 0.91 | ABL1 (0.83) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27804468 | 0.90 | ABL1 (0.82) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27782896 | 0.90 | ABL1 (1.00) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27782924 | 0.90 | ABL1 (0.81) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL5023657 | 0.90 | ABL1 (0.80) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27782910 | 0.89 | ABL1 (0.80) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27783033 | 0.89 | ABL1 (0.81) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27804469 | 0.88 | ABL1 (0.79) | ABL1BCRPDGFRBKITBRAF | |
| SCHEMBL27804467 | 0.88 | ABL1 (0.82) | ABL1BCRPDGFRBKITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747330-B | Pyridyl thiazole amine compound and medicinal composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2012-03-21 | — | — | CN | disclosed |
| CN-101747330-A | Pyridyl thiazole amine compound and medicinal composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2010-06-23 | — | — | CN | disclosed |