Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.31 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601629 | 0.82 | ESR1 (0.41) | TTRHTTESR1POLBTHRB | |
| SCHEMBL23601635 | 0.80 | ESR1 (0.46) | TTRKMT2AHTTESR1POLB | |
| SCHEMBL30486727 | 0.76 | TTR (0.54) | TTRERN1MEN1KMT2AHTT | |
| SCHEMBL7034885 | 0.76 | TTR (0.54) | TTRERN1MEN1KMT2AHTT | |
| Methacrylic Acid SCHEMBL27783148 | 0.76 | TTR (0.48) | TTRERN1MEN1KMT2AHTT | |
| SCHEMBL22991362 | 0.74 | TTR (0.61) | TTRERN1MEN1KMT2AHTT | |
| SCHEMBL26794108 | 0.73 | ELANE (0.45) | TTRMEN1KMT2AHTTBLM | |
| SCHEMBL27397892 | 0.72 | TTR (0.48) | TTRERN1MEN1KMT2AHTT | |
| SCHEMBL30289413 | 0.72 | TTR (0.48) | TTRERN1MEN1KMT2AHTT | |
| SCHEMBL25756238 | 0.72 | TTR (0.48) | TTRKMT2AESR1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113329693-A | Laminated manufacture of radiological prostheses | 斯特拉塔西斯公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-101511396-B | Bone cement compositions comprising indicators and related methods | KYPHON INC | 2013-04-17 | — | — | CN | disclosed |
| CN-101511396-A | Bone cement compositions comprising indicators and related methods | KYPHON INC (CH) | 2009-08-19 | — | — | CN | disclosed |