Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601629 | 0.95 | ESR1 (0.41) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL23601572 | 0.88 | TSHR (0.42) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL23601639 | 0.83 | TSHR (0.45) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL6886176 | 0.82 | THRB (0.41) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL29623140 | 0.82 | THRB (0.41) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL27783147 | 0.80 | TTR (0.44) | ESR1POLBHTTKMT2ATTR | |
| SCHEMBL22168539 | 0.80 | THRB (0.40) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL22193458 | 0.79 | TSHR (0.44) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL10725906 | 0.77 | THRB (0.45) | ESR1TSHRTDP1POLBAPEX1 | |
| SCHEMBL22193461 | 0.76 | TSHR (0.50) | ESR1TSHRTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210200093-A1 | COATING COMPOSITION FOR PHOTORESIST UNDERLAYER | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2021-07-01 | — | — | US | disclosed |