Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.66 |
| ▸ | TOP2A | P11388 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922295 | 0.91 | SMN1; SMN2 (0.67) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4924375 | 0.87 | TOP2A (0.67) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4923493 | 0.83 | SMN1; SMN2 (0.78) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4921781 | 0.80 | RAB9A (0.69) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4925939 | 0.78 | RAB9A (0.73) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4913026 | 0.78 | SMN1; SMN2 (0.73) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4923596 | 0.78 | RAB9A (0.73) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4923804 | 0.76 | MKNK1 (0.73) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4913665 | 0.75 | SMN1; SMN2 (0.71) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4922091 | 0.74 | RAB9A (0.63) | BRAFTOP2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1556808-B | Containing radicals based on N6Cosmetic preparation of heterocyclic compound of-substituted adenine | UZTAF EXPERIMENT PLANT SOC CZ V | 2010-04-28 | — | — | CN | disclosed |