⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminoserine SCHEMBL8333262 | 1.00 | — | — | |
| Aminoserine SCHEMBL277837 | 1.00 | — | — | |
| Aminoserine SCHEMBL853082 | 0.97 | — | — | |
| Aminoserine SCHEMBL853081 | 0.97 | — | — | |
| Aminoserine SCHEMBL5114875 | 0.97 | — | — | |
| Aminoserine SCHEMBL8506214 | 0.94 | — | — | |
| Aminoserine SCHEMBL15668067 | 0.94 | SLC1A1 (0.37) | — | |
| Aminoserine SCHEMBL8506211 | 0.94 | — | — | |
| Aminoserine SCHEMBL3166789 | 0.89 | SLC1A1 (0.34) | — | |
| Aminoserine SCHEMBL17491742 | 0.89 | LMNA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640114-B | PD-L1 targeted molecular probe and preparation method and application thereof | 江苏省原子医学研究所 | 2024-05-14 | — | — | CN | claimed |
| CN-116640114-A | PD-L1 targeted molecular probe and preparation method and application thereof | 江苏省原子医学研究所 | 2023-08-25 | — | — | CN | claimed |
| CN-112839664-A | Composition for preventing or treating keloid or hypertrophic scar | 太高赛恩斯株式会社 | 2021-05-25 | — | — | CN | claimed |
| CN-111533708-B | Preparation method of chiral N-tert-butoxycarbonylmorpholine-3-carboxylic acid | 上海馨远医药科技有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-111533708-A | Preparation method of chiral N-tert-butoxycarbonylmorpholine-3-carboxylic acid | 上海馨远医药科技有限公司 | 2020-08-14 | — | — | CN | claimed |
| US-20100204265-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections | GENELABS TECHNOLOGIES, INC. | 2010-08-12 | — | — | US | claimed |
| CN-101448784-A | (2R)-2-[(4-sulfonyl)aminophenyl]propanamides and pharmaceutical compositions containing them | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-06-03 | — | — | CN | claimed |
| CN-101228133-A | Heteroaroyl-substituted serineamides | BASF AG (DE) | 2008-07-23 | — | — | CN | claimed |
| CN-101228116-A | Benzoyl-substituted serineamides | BASF AG (DE) | 2008-07-23 | — | — | CN | claimed |
| CN-101023069-A | Benzoyl-substituted serine amides | BASF AG (DE) | 2007-08-22 | — | — | CN | claimed |
| EP-1433778-A1 | Use of nitriles as rotamase inhibitors | Jerini AG (DE) | 2004-06-30 | — | — | EP | claimed |
| EP-1104304-A1 | MULTIVALENT AVB3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 2001-06-06 | — | — | EP | claimed |
| EP-1070085-A1 | DUAL A v?b 3? AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 2001-01-24 | — | — | EP | claimed |
| WO-2000009143-A1 | MULTIVALENT AVB3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 2000-02-24 | — | — | WO | claimed |
| WO-1999051638-A1 | DUAL Avb3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 1999-10-14 | — | — | WO | claimed |
| US-5519000-A | OLIGOPEPTIDE | CENTECOR, INC. (US) | 1996-05-21 | — | — | US | claimed |
| US-5486595-A | Tumor necrosis factor inhibitors | CENTECOR, INC. (US) | 1996-01-23 | — | — | US | claimed |
| WO-1995026744-A1 | TUMOR NECROSIS FACTOR INHIBITORS | CENTOCOR, INC. (US) | 1995-10-12 | — | — | WO | claimed |
| US-5215897-A | Reacting amino acid amide with a culture of microorganisms Enterobacter cloacae or Pseudomonas species and mutant strains that produce L-amylase activity | NITTO CHEMICAL INDUSTRIES CO., LTD. (JP) | 1993-06-01 | — | — | US | claimed |
| EP-0203031-A2 | Biologically active lysine containing octapeptides | The Administrators of The Tulane University Educational Fund (US) | 1986-11-26 | — | — | EP | claimed |