Phenylacetic Acid

Phenylacetic Acid

SCHEMBL27783752

O=C([O-])Cc1ccccc1.O=C([O-])Cc1ccccc1.[Pd+2]

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.71
CES2 O00748 2/20 0.71
AKR1B1 P15121 1/20 0.64
FNTA P49354 1/20 0.58
FNTB P49356 1/20 0.58
HDAC8 Q9BY41 2/20 0.54
HDAC6 Q9UBN7 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetic Acid SCHEMBL4452245 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL11772449 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL78312 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL11248694 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL6547052 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL1685642 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL6930085 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL7214226 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL3477184 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB
Phenylacetic Acid SCHEMBL62440 0.95 CES1 (0.71) CES1CES2AKR1B1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101716523-A Palladium phenylacetate composite phase transfer catalysis system synthesized by carbonylation of benzyl chloride YANAN CHANGTAI PHARMACEUTICAL 2010-06-02 CN disclosed
CN-101716523-A Palladium phenylacetate composite phase transfer catalysis system synthesized by carbonylation of benzyl chloride YANAN CHANGTAI PHARMACEUTICAL 2010-06-02 CN disclosed