SCHEMBL2778432

SCHEMBL2778432

O=C1OC(=O)c2c1c(-c1ccccc1)c(-c1ccccc1)c(-c1ccccc1)c2-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
LMNA P02545 1/20 0.57
HTT P42858 1/20 0.57
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 3/20 0.42
PTGS2 P35354 2/20 0.42
PDGFRA P16234 1/20 0.41
MAPK8 P45983 1/20 0.41
CDK5 Q00535 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CTRC Q99895 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CHEK1 O14757 1/20 0.39
TYMP P19971 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1902220 0.97 MAPT (0.55) MAPTLMNAHTTALOX15TDP1
SCHEMBL1899869 0.91 HTT (0.48) MAPTLMNAHTTALOX15TDP1
SCHEMBL15119598 0.87 MAPT (0.50) MAPTLMNAHTTALOX15TDP1
SCHEMBL10519343 0.85 ALDH1A1 (0.54) MAPTLMNAHTTALOX15TDP1
SCHEMBL15064384 0.85 MAPT (0.43) MAPTLMNAHTTTDP1ALDH1A1
SCHEMBL21537234 0.83 MAPT (0.42) MAPTLMNAHTTALOX15TDP1
SCHEMBL18919401 0.80 MAPT (0.48) MAPTLMNAHTTALOX15TDP1
SCHEMBL30753514 0.80 MAPT (0.48) MAPTLMNAHTTALOX15TDP1
SCHEMBL11299394 0.79 CYP1A2 (0.47) MAPTLMNATDP1ALDH1A1PTGS2
SCHEMBL11006647 0.79 ALDH1A1 (0.58) MAPTLMNAHTTALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118236866-A Chitin chain piece nano fluid film and preparation method and application thereof 湖北大学 2024-06-25 CN claimed
CN-114093675-A Electrolyte for 600V ultrahigh voltage aluminum electrolytic capacitor, preparation method thereof and application of electrolyte in aluminum electrolytic capacitor 赣州富之庆电子科技有限公司 2022-02-25 CN claimed
CN-109456596-B High-temperature nylon automobile material 深圳市晨宇丰塑胶新材料有限公司 2021-06-29 CN claimed
CN-109467903-B Polycarbonate composition for charging pile 惠州市中海源新材料科技有限公司 2020-12-08 CN claimed
CN-109535664-B High polymer material for connector 惠州市中海源新材料科技有限公司 2020-12-01 CN claimed
CN-106478968-B A kind of preparation method of nanometer of Kapton 陕西科技大学 2019-06-28 CN claimed
CN-109535664-A A kind of connector high molecular material 惠州市中海源新材料科技有限公司 2019-03-29 CN claimed
CN-109467903-A A kind of charging pile polycarbonate compositions 惠州市中海源新材料科技有限公司 2019-03-15 CN claimed
CN-109456596-A A kind of high-temperature nylon automotive material 惠州市中海源新材料科技有限公司 2019-03-12 CN claimed
CN-106478968-A A kind of preparation method of nanometer of Kapton 陕西科技大学 2017-03-08 CN claimed
US-7595108-B2 Nanoparticles comprising a metal core and an organic double coating useful as catalysts and device containing the nanoparticles COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2009-09-29 US claimed
US-20080226895-A1 Use of Nanoparticles With a Metal Core and an Organic Double Coating as Catalysts and Nanoparticles That Are Useful as Catalysts COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-09-18 US claimed
CN-1838994-A Use of nanoparticles having a metal core and an organic double coating as a catalyst, and nanoparticles usable as a catalyst COMMISSARIAT ENERGIE ATOMIQUE (FR) 2006-09-27 CN claimed
US-6340528-B1 USEFUL IN IONOGRAPHIC OR ELECTROPHOTOGRAPHIC APPARATUSES AND USEFUL IN HYBRID SCAVENGELESS DEVELOPMENT UNITS XEROX CORPORATION 2002-01-22 US claimed
US-4338222-A Semiconductive organic compositions XEROX CORPORATION (US) 1982-07-06 US claimed
EP-3723160-B1 SEPARATOR FOR LITHIUM-SULFUR BATTERY AND LITHIUM-SULFUR BATTERY INCLUDING SAME LG ENERGY SOLUTION LTD (KR) 2025-03-26 EP disclosed
CN-119253073-A High-voltage electrolyte and lithium ion battery 合肥国轩高科动力能源有限公司 2025-01-03 CN disclosed
US-4338222-A Semiconductive organic compositions XEROX CORPORATION (US) 1982-07-06 US disclosed
US-4289839-A BLOCKED COUPLER LIBERATED BY PHOTOCHEMICALLY FORMED ACID JAMES RIVER GRAPHICS, INC. (US) 1981-09-15 US disclosed
US-4259383-A PEROXY COMPOUNDS STERLING DRUG INC. (US) 1981-03-31 US disclosed