Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 4/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784334 | 0.84 | CA1 (0.36) | CA1CA2BRAFSLC22A12KIF11 | |
| SCHEMBL27784411 | 0.83 | CA1 (0.42) | CA1CA2HSD11B1BRAFSLC22A12 | |
| SCHEMBL2419202 | 0.82 | CA1 (0.37) | CA1CA2BRAFSLC22A12KIF11 | |
| Sulfamide SCHEMBL2410942 | 0.82 | MELK (0.38) | HSD11B1ADORA2AADORA1MEN1USP2 | |
| SCHEMBL27806392 | 0.80 | KDM4E (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL1620690 | 0.80 | CA1 (0.46) | CA1CA2SLC22A12KIF11LMNA | |
| SCHEMBL27784300 | 0.79 | CA1 (0.39) | CA1CA2BRAFSLC22A12KIF11 | |
| SCHEMBL2413234 | 0.78 | PTGES2 (0.42) | CA1CA2BRAFALDH1A1MAPT | |
| SCHEMBL2417704 | 0.78 | CA2 (0.43) | CA1CA2SLC22A12KIF11MEN1 | |
| SCHEMBL2413576 | 0.78 | CA2 (0.43) | CA1CA2SLC22A12KIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-101779124-B | Modulation of chemosensory receptors and ligands associated therewith | 西诺米克斯公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-107365319-A | The regulation carried out to actinism acceptor and relative part | 西诺米克斯公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-101779124-A | modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC | 2010-07-14 | — | — | CN | disclosed |