SCHEMBL27784451

SCHEMBL27784451

N#Cc1ccccc1NS(N)(=O)=O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.53
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
KIF11 P52732 1/20 0.50
KDM4E B2RXH2 3/20 0.45
GAA P10253 3/20 0.45
TSHR P16473 2/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
SLC40A1 Q9NP59 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HTT P42858 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28311196 0.86 CA1 (0.43) SLC22A12CA1CA2CA12CA9
SCHEMBL2478549 0.81 SLC22A12 (0.53) SLC22A12CA1CA2CA12CA9
SCHEMBL1291534 0.81 SLC22A12 (0.53) SLC22A12CA1CA2CA12CA9
SCHEMBL27182691 0.79 SLC22A12 (0.51) SLC22A12CA1CA2CA12CA9
SCHEMBL28184925 0.79 KIF11 (0.40) SLC22A12CA1CA2CA12CA9
SCHEMBL2417899 0.79 KIF11 (0.71) CA1CA2KIF11KDM4EGAA
SCHEMBL31377994 0.78 SLC22A12 (0.61) SLC22A12CA2KIF11KDM4EGAA
Sulfuric Acid SCHEMBL20984556 0.76 CA12 (0.49) SLC22A12CA1CA2CA12CA9
SCHEMBL2420510 0.75 CA1 (0.46) SLC22A12CA1CA2CA12CA9
SCHEMBL2419259 0.75 KIF11 (0.59) SLC22A12CA1CA2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110115365-A The adjusting that actinism receptor and relative ligand are carried out 西诺米克斯公司 2019-08-13 CN disclosed
CN-103153096-A Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers SENOMYX INC 2013-06-12 CN disclosed
CN-101779124-A modulation of chemosensory receptors and ligands associated therewith SENOMYX INC 2010-07-14 CN disclosed