Ethyne

Ethyne

SCHEMBL27784530

C#C.c1cnc2nccnc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
MAPT P10636 5/20 0.46
KDM4E B2RXH2 4/20 0.46
POLB P06746 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
BCHE P06276 2/20 0.37
ACHE P22303 2/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
CYP3A4 P08684 2/20 0.37
USP2 O75604 1/20 0.37
HTT P42858 4/20 0.35
LMNA P02545 3/20 0.35
HSP90AA1 P07900 3/20 0.35
CASP1 P29466 2/20 0.35
HSP90AB1 P08238 2/20 0.35
HIF1A Q16665 2/20 0.35
TP53 P04637 2/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358342 0.95 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EPOLBNPC1
SCHEMBL29408294 0.95 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EPOLBNPC1
SCHEMBL88611 0.95 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EPOLBNPC1
Biphenyl SCHEMBL27984062 0.83 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EPOLBNPC1
Furan SCHEMBL29037471 0.81 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EPOLBNPC1
Piperazine SCHEMBL28097858 0.81 ALDH1A1 (0.43) ALDH1A1MAPTKDM4ECYP3A4LMNA
SCHEMBL14856779 0.78 ALDH1A1 (0.40) ALDH1A1MAPTKDM4EPOLBNPC1
Phthalazine SCHEMBL11491846 0.78 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EPOLBNPC1
SCHEMBL8194 0.76 ALDH1A1 (0.67) ALDH1A1MAPTKDM4EPOLBNPC1
SCHEMBL30099834 0.76 ALDH1A1 (0.67) ALDH1A1MAPTKDM4EPOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107004768-B Organic semiconductor composition containing a liquid medium 巴斯夫欧洲公司 2020-08-21 CN disclosed
CN-101772492-A N BASF SE 2010-07-07 CN disclosed