SCHEMBL277846

SCHEMBL277846

NC(=O)C1CCC1C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.50
GABRR1 P24046 3/20 0.40
GRM4 Q14833 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
OR51E2 Q9H255 1/20 0.36
PSEN1 P49768 3/20 0.35
PSEN2 P49810 3/20 0.35
APH1B Q8WW43 3/20 0.35
NCSTN Q92542 3/20 0.35
APH1A Q96BI3 3/20 0.35
PSENEN Q9NZ42 3/20 0.35
SLC1A2 P43004 2/20 0.35
SLC1A1 P43005 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38651938 1.00 EPHX1 (0.50) EPHX1GABRR1GRM4TDP1ALDH1A1
SCHEMBL38651937 1.00 EPHX1 (0.50) EPHX1GABRR1GRM4TDP1ALDH1A1
SCHEMBL38652299 1.00 EPHX1 (0.50) EPHX1GABRR1GRM4TDP1ALDH1A1
SCHEMBL13544498 0.87 GABRR1 (0.52) EPHX1GABRR1GRM4ALDH1A1LMNA
SCHEMBL38652047 0.87 GABRR1 (0.52) EPHX1GABRR1GRM4ALDH1A1LMNA
SCHEMBL9800070 0.86 EPHX1 (0.67) EPHX1GRM4ALDH1A1LMNAPSEN1
SCHEMBL13557474 0.86 EPHX1 (0.67) EPHX1GRM4ALDH1A1LMNAPSEN1
SCHEMBL7362431 0.86 EPHX1 (0.59) EPHX1GRM4ALDH1A1LMNAPSEN1
SCHEMBL2343227 0.86 EPHX1 (0.59) EPHX1GRM4ALDH1A1LMNAPSEN1
SCHEMBL1570434 0.86 EPHX1 (0.67) EPHX1GRM4ALDH1A1LMNAPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335381-A Bifunctional degradants of interleukin-1 receptor-associated kinase and therapeutic uses thereof 新锐思生物制药股份有限公司 2022-11-11 CN disclosed
EP-3217222-B1 METALLIC TONER COMPOSITIONS XEROX CORP (US) 2021-11-10 EP disclosed
EP-3474075-A1 METALLIC TONER CARRIER Xerox Corporation (US) 2019-04-24 EP disclosed
US-20190113859-A1 Metallic Toner Carrier XEROX CORPORATION 2019-04-18 US disclosed
EP-1936440-B1 METHOD OF MAKING A LOW MELT TONER XEROX CORP (US) 2018-04-04 EP disclosed
US-9874825-B2 Continuous coalescence processes XEROX CORPORATION (US) 2018-01-23 US disclosed
US-9809698-B2 Robust method for producing latex seed particles XEROX CORPORATION (US) 2017-11-07 US disclosed
US-9791797-B2 Metallic toner compositions XEROX CORPORATION (US) 2017-10-17 US disclosed
US-20170261877-A1 Metallic Toner Compositions XEROX CORPORATION 2017-09-14 US disclosed
EP-3217222-A1 METALLIC TONER COMPOSITIONS Xerox Corporation (US) 2017-09-13 EP disclosed
US-20090208864-A1 SOLVENT-FREE PHASE INVERSION PROCESS FOR PRODUCING RESIN EMULSIONS XEROX CORPORATION (US) 2009-08-20 US disclosed
EP-2090611-A2 Solvent-free phase inversion process for producing resin emulsions Xerox Corporation (US) 2009-08-19 EP disclosed
US-7547499-B2 amorphous polyester material, and a crystalline polyester; amorphous polymer material has an acid number that is greater than an acid number of the crystalline; exhibit a low melt temperature while simultaneously exhibiting excellent relative humidity sensitivity regarding charging properties XEROX CORPORATION (US) 2009-06-16 US disclosed
US-20080153027-A1 amorphous polyester material, and a crystalline polyester; amorphous polymer material has an acid number that is greater than an acid number of the crystalline; exhibit a low melt temperature while simultaneously exhibiting excellent relative humidity sensitivity regarding charging properties XEROX CORPORATION (US) 2008-06-26 US disclosed
EP-1936440-A2 Low melt toner Xerox Corporation (US) 2008-06-25 EP disclosed
US-6830860-B2 Comprised of branched amorphous and crystalline resins and colorant; low fixing temperature; broad fusing latitude; transparency; offset resistance XEROX CORPORATION 2004-12-14 US disclosed
EP-1441260-A1 Toner compositions and processes thereof Xerox Corporation (US) 2004-07-28 EP disclosed
US-20040142266-A1 Toner compositions and processes thereof XEROX CORPORATION 2004-07-22 US disclosed
US-6022918-A POLYETHYLENE WAX HAVING A MOLECULAR MASS OF FROM 3000 TO 6000 G/MOL, AND A WETTING AGENT, COMPRISING A FATTY ALCOHOL ETHOXYLATE. BASF COATINGS AG (DE) 2000-02-08 US disclosed
US-5084304-A Heat resistant coating applied to a metal, a heat resistant material polymer such as a blend of a polyesterimide, a polyhydantoin, a polyamide, a polyamideimide copolymer and a polybismaleimide BASF LACKE & FARBEN AG (DE) 1992-01-28 US disclosed