Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27764503 | 0.87 | ADK (0.51) | PRMT5WDR77METTL3ADK | |
| SCHEMBL20419326 | 0.84 | PRMT5 (0.47) | PRMT5WDR77ADK | |
| SCHEMBL23982307 | 0.84 | PRMT5 (0.47) | PRMT5WDR77ADK | |
| SCHEMBL20419292 | 0.84 | PRMT5 (0.47) | PRMT5WDR77ADK | |
| SCHEMBL20692015 | 0.83 | PRMT5 (0.44) | PRMT5WDR77METTL3METTL14ADK | |
| SCHEMBL13603565 | 0.83 | PRMT5 (0.44) | PRMT5WDR77METTL3METTL14ADK | |
| SCHEMBL28780630 | 0.79 | ADK (0.43) | ADK | |
| SCHEMBL14134779 | 0.79 | ADK (0.43) | ADK | |
| SCHEMBL27764457 | 0.79 | ADK (0.58) | ADK | |
| SCHEMBL22002059 | 0.76 | PRMT5 (0.39) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600726-A | The novel nucleoside analogs that is used for the treatment of virus infection | NOVARTIS AG (CH) | 2009-12-09 | — | — | CN | disclosed |