Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | BUB1 | O43683 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893100 | 0.76 | F2R (0.64) | F2RALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL27808021 | 0.73 | NAMPT (0.36) | F2RALDH1A1KMT2APKMCASP3 | |
| SCHEMBL354704 | 0.72 | — | — | |
| SCHEMBL27402078 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KMT2APKMCASP3SENP7 | |
| SCHEMBL11582158 | 0.70 | KMT2A (0.66) | ALDH1A1KMT2APKMCASP3SENP7 | |
| SCHEMBL5394754 | 0.70 | KMT2A (0.71) | ALDH1A1KMT2APKMCASP3SENP7 | |
| SCHEMBL27984069 | 0.69 | KMT2A (0.69) | ALDH1A1KMT2APKMCASP3SENP7 | |
| Ammonia Solution, Strong SCHEMBL28083920 | 0.69 | KMT2A (0.69) | ALDH1A1KMT2APKMCASP3SENP7 | |
| SCHEMBL28520017 | 0.69 | KMT2A (0.69) | ALDH1A1KMT2APKMCASP3SENP7 | |
| SCHEMBL27646879 | 0.69 | KMT2A (0.69) | ALDH1A1KMT2APKMCASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101796038-B | Oxazole tyrosine kinase inhibitors | SAREUM LTD. (GB) | 2014-10-29 | — | — | CN | disclosed |
| CN-101796038-A | Oxazole tyrosine kinase inhibitors | SAREUM LTD | 2010-08-04 | — | — | CN | disclosed |