SCHEMBL27786356

SCHEMBL27786356

CCCNC1=CC=CNC=C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13370047 0.65
SCHEMBL27835768 0.64
SCHEMBL22292613 0.64 GAA (0.31)
SCHEMBL27795108 0.64
SCHEMBL7178297 0.64 LMNA (0.31)
SCHEMBL18727733 0.61
SCHEMBL7360580 0.61
SCHEMBL20630387 0.61
SCHEMBL24619980 0.60 KDM4E (0.33) ALDH1A1
SCHEMBL24916721 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101594868-B Pharmaceutical composition with antipsychotic, antidepressant or antiepileptic activity and reduced side effects GENE RES LAB INC US N 2012-12-12 CN disclosed
CN-101636391-B Novel prophylactic and/or therapeutic agent for neurogenic pain ASTELLAS PHARMA INC JP 2012-11-28 CN disclosed
CN-101657211-A Use of lhrh antagonists for the treatment of lower urinary tract symptoms, in particular overactive bladder and/or detrusor overactivity AETERNA ZENTARIS GMBH DE 2010-02-24 CN disclosed
CN-101636391-A Novel prophylactic and/or therapeutic agent for neurogenic pain ASTELLAS PHARMA INC 2010-01-27 CN disclosed
CN-101594868-A Pharmaceutical composition with antipsychotic, antidepressant or antiepileptic activity and reduced side effects N GENE RES LAB INC (US) 2009-12-02 CN disclosed