SCHEMBL2778637

SCHEMBL2778637

CN(C)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
TSHR P16473 4/20 0.61
HSD17B10 Q99714 2/20 0.61
ALOX15 P16050 2/20 0.61
MAPT P10636 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
CHKA P35790 2/20 0.57
MAPK1 P28482 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
RELA Q04206 1/20 0.56
RAB9A P51151 3/20 0.52
HPGD P15428 3/20 0.52
NPC1 O15118 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NOX1 Q9Y5S8 1/20 0.52
LMNA P02545 2/20 0.50
CYP3A4 P08684 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
NPY1R P25929 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15125583 1.00 ALDH1A1 (0.61) ALDH1A1TSHRHSD17B10ALOX15MAPT
Phosphine SCHEMBL28255440 0.97 ALDH1A1 (0.58) ALDH1A1TSHRHSD17B10ALOX15MAPT
Hydrochloric Acid SCHEMBL2861594 0.97 ALDH1A1 (0.58) ALDH1A1TSHRHSD17B10ALOX15MAPT
SCHEMBL29239352 0.97 ALDH1A1 (0.58) ALDH1A1TSHRHSD17B10ALOX15MAPT
SCHEMBL17735817 0.93 ALDH1A1 (0.52) ALDH1A1TSHRHSD17B10ALOX15MAPT
SCHEMBL26378087 0.91 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10ALOX15MAPT
SCHEMBL14065149 0.91 PNPLA2 (0.53) ALDH1A1TSHRHSD17B10ALOX15MAPT
SCHEMBL124209 0.88 ALDH1A1 (0.79) ALDH1A1TSHRHSD17B10ALOX15MAPT
SCHEMBL11547412 0.88 ALDH1A1 (0.79) ALDH1A1TSHRHSD17B10ALOX15MAPT
SCHEMBL16837157 0.87 ALDH1A1 (0.52) ALDH1A1TSHRHSD17B10ALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217324-A Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2023-06-06 CN claimed
CN-108947948-B N-aryl naphthofuranone imine compound and synthetic method thereof 湖南大学 2021-07-20 CN claimed
EP-2859069-B1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2020-10-14 EP claimed
EP-1565436-A4 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS INCYTE CORP (US) 2007-07-18 EP claimed
JP-2006516145-A 2006-06-22 JP claimed
EP-1565436-A2 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS INCYTE CORPORATION (US) 2005-08-24 EP claimed
WO-2004050024-A2 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS INCYTE CORPORATION (US) 2004-06-17 WO claimed
JP-2182484-A None JP disclosed
CN-119191946-B Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide 南京工业大学 2026-05-15 CN disclosed
EP-4130195-B1 COMPOSITION AND LIGHT-EMITTING ELEMENT CONTAINING SAME SUMITOMO CHEMICAL CO (JP) 2025-09-03 EP disclosed
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-01-14 US disclosed
CN-119191946-A Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide 南京工业大学 2024-12-27 CN disclosed
WO-2024262927-A1 NOVEL FLUORESCENT COMPOUND, AND COMPOSITION FOR DETECTING GINGIPAIN, COMPOSITION FOR DIAGNOSING PORPHYROMONAS GINGIVALIS INFECTION, OR ANTIBACTERIAL COMPOSITION AGAINST PORPHYROMONAS GINGIVALIS USING SAME 한국과학기술연구원 2024-12-26 WO disclosed
WO-1998037052-A1 PREPARATION OF ARYL BROMOARYL KETONES AND CARBOXYLIC DERIVATIVES THEREOF ALBEMARLE CORPORATION (US) 1998-08-27 WO disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed
CN-1120053-A trisazo black dye YONGGUANG CHEMICAL INDUSTRY CO (CN) 1996-04-10 CN disclosed
JP-H02182484-A RECORDING SHEET FUJI PHOTO FILM CO LTD 1990-07-17 JP disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
EP-0012946-A1 Process for the production of winding tapes for the high voltage insulation of electric machines and apparatuses, and winding tape for making an insulating envelope for electric conductors KRAFTWERK UNION AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs MERTK, ERBB2, SRC ALDH1A1 3115/4885TSHR 1878/4885HSD17B10 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.