Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 6/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166390 | 0.86 | ACACB (0.60) | CYP1A2CYP2D6APEX1PMP22ACACB | |
| SCHEMBL8729705 | 0.84 | NPC1 (0.58) | NPC1RAB9AACACBSIGMAR1LMNA | |
| SCHEMBL11689625 | 0.84 | NPC1 (0.58) | NPC1RAB9AACACBSIGMAR1LMNA | |
| SCHEMBL24609344 | 0.83 | NPC1 (0.79) | NPC1RAB9ASIGMAR1LMNATAAR1 | |
| SCHEMBL2543698 | 0.83 | NPC1 (0.79) | NPC1RAB9ASIGMAR1LMNATAAR1 | |
| SCHEMBL165893 | 0.83 | ACACB (0.58) | CYP1A2CYP2D6NPC1RAB9AAPEX1 | |
| SCHEMBL164441 | 0.82 | ACACB (0.63) | NPC1RAB9AACACBSIGMAR1LMNA | |
| SCHEMBL23275246 | 0.82 | ACACB (0.63) | NPC1RAB9AACACBSIGMAR1LMNA | |
| SCHEMBL4325972 | 0.82 | ACACB (0.66) | NPC1RAB9AACACBLMNATAAR1 | |
| Hydrochloric Acid SCHEMBL4323384 | 0.81 | NPC1 (0.76) | NPC1RAB9ASIGMAR1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605758-A | Methods of treating hepatitis C | PTC THERAPEUTICS INC (US) | 2009-12-16 | — | — | CN | disclosed |