Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825426 | 0.88 | ACACB (0.83) | ACACBLMNA | |
| SCHEMBL4319657 | 0.85 | LOXL2 (0.53) | ACACBNPC1RAB9ATDP1 | |
| SCHEMBL8729705 | 0.84 | NPC1 (0.58) | ACACBNPC1RAB9ALMNATAAR1 | |
| SCHEMBL11689625 | 0.84 | NPC1 (0.58) | ACACBNPC1RAB9ALMNATAAR1 | |
| SCHEMBL255724 | 0.83 | ACACB (0.76) | ACACBADRB1ADRB3LMNA | |
| SCHEMBL24609344 | 0.83 | NPC1 (0.79) | NPC1RAB9AALDH1A1LMNATP53 | |
| SCHEMBL2543698 | 0.83 | NPC1 (0.79) | NPC1RAB9AALDH1A1LMNATP53 | |
| SCHEMBL27786644 | 0.82 | CYP1A2 (0.58) | ACACBNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL23275246 | 0.82 | ACACB (0.63) | ACACBNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL164441 | 0.82 | ACACB (0.63) | ACACBNPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |