Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.38 |
| ▸ | KIT | P10721 | 4/20 | 0.38 |
| ▸ | BCR | P11274 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | FGR | P09769 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788420 | 0.85 | LCK (0.42) | LCKABL1KITBCRJAK3 | |
| SCHEMBL27792012 | 0.85 | LCK (0.42) | LCKABL1KITBCRJAK3 | |
| SCHEMBL14142362 | 0.81 | LCK (0.52) | LCKABL1KITBCRJAK3 | |
| SCHEMBL14142008 | 0.78 | LCK (0.51) | LCKABL1KITBCRJAK3 | |
| SCHEMBL14141840 | 0.77 | LCK (0.50) | LCKABL1KITBCRJAK3 | |
| SCHEMBL14141667 | 0.76 | LCK (0.47) | LCKABL1KITBCRJAK3 | |
| SCHEMBL27788357 | 0.76 | LCK (0.42) | LCKABL1KITBCRJAK3 | |
| SCHEMBL27810250 | 0.75 | SRC (0.68) | LCKABL1KITBCRJAK3 | |
| SCHEMBL14142219 | 0.73 | LCK (0.47) | LCKABL1KITBCRJAK3 | |
| SCHEMBL14141841 | 0.72 | ALDH1A1 (0.44) | POLBSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101812060-B | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIOENGINEERING TECHNOLOGY CO LTD | 2011-08-17 | — | — | CN | claimed |
| CN-101812060-A | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD | 2010-08-25 | — | — | CN | claimed |
| CN-101812060-B | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIOENGINEERING TECHNOLOGY CO LTD | 2011-08-17 | — | — | CN | disclosed |
| CN-101812060-A | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD | 2010-08-25 | — | — | CN | disclosed |