Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17920373 | 0.87 | GPR84 (0.62) | GPR84CYP2A6CFTRAHRMAOA | |
| Ethoxycarbonyl Group SCHEMBL27942879 | 0.82 | GPR84 (0.46) | GPR84CYP2A6AHRMAOAMEN1 | |
| SCHEMBL10289958 | 0.80 | GPR84 (0.62) | GPR84CYP2A6CFTRAHRMAOA | |
| Ethoxycarbonyl Group SCHEMBL27431556 | 0.80 | GPR84 (0.44) | GPR84CYP2A6AHRMAOAMEN1 | |
| Ethoxycarbonyl Group SCHEMBL28658781 | 0.80 | AHR (0.62) | GPR84CYP2A6AHRMAOAMEN1 | |
| Ethoxycarbonyl Group SCHEMBL27447133 | 0.80 | AHR (0.62) | GPR84CYP2A6AHRMAOACTNNB1 | |
| Ethoxycarbonyl Group SCHEMBL28038347 | 0.78 | CYP2A6 (0.39) | GPR84CYP2A6MAOAMEN1POLB | |
| Ethoxycarbonyl Group SCHEMBL27648730 | 0.78 | CSNK2A1 (0.46) | GPR84CYP2A6AHRMAOAMEN1 | |
| Ethoxycarbonyl Group SCHEMBL28038686 | 0.77 | CYP2A6 (0.45) | CYP2A6AHRMAOA | |
| Ethoxycarbonyl Group SCHEMBL27526972 | 0.75 | CYP2A6 (0.46) | CYP2A6AHRMAOAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101821252-A | The indole derivatives and the using method thereof that replace | CHERING CORP | 2010-09-01 | — | — | CN | disclosed |