Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MYLK2 | Q9H1R3 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | BMP2K | Q9NSY1 | 2/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634380 | 0.84 | TGFBR1 (0.48) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL29505431 | 0.83 | IRAK4 (0.44) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL13162322 | 0.83 | IRAK4 (0.44) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL31268286 | 0.82 | IRAK4 (0.43) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL2080592 | 0.82 | IRAK4 (0.43) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL27790485 | 0.80 | TGFBR1 (0.43) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL13270402 | 0.80 | IRAK4 (0.42) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL28239305 | 0.79 | BACE1 (0.46) | TGFBR1IRAK4GSK3BDYRK1APIK3C3 | |
| SCHEMBL29613007 | 0.78 | TGFBR1 (0.42) | TGFBR1IRAK4GSK3BPIK3C3SREBF2 | |
| SCHEMBL16698999 | 0.78 | TGFBR1 (0.42) | TGFBR1IRAK4GSK3BPIK3C3SREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101835764-B | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-09-19 | — | — | CN | disclosed |
| CN-101835764-A | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC | 2010-09-15 | — | — | CN | disclosed |