SCHEMBL27790697

SCHEMBL27790697

O=S(=O)(CCF)NCCC(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.63
PGR P06401 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3590877 0.88 NR3C1 (0.75) NR3C1PGR
SCHEMBL27790743 0.84 NR3C1 (0.70) NR3C1PGR
SCHEMBL27769314 0.83 NR3C1 (0.57) NR3C1
SCHEMBL27790698 0.82 NR3C1 (0.58) NR3C1
SCHEMBL3594470 0.82 NR3C1 (0.59) NR3C1PGR
SCHEMBL3591202 0.81 NR3C1 (0.70) NR3C1PGR
SCHEMBL27769315 0.79 NR3C1 (0.59) NR3C1PGR
SCHEMBL3587382 0.78 NR3C1 (0.71) NR3C1PGR
SCHEMBL3593838 0.78 NR3C1 (1.00) NR3C1PGR
SCHEMBL3593839 0.78 NR3C1 (1.00) NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101573340-A Modulators of glucocorticoid receptor AP-1 and/or NF-kB activity and uses thereof BRISTOL MYERS SQUIBB CO (US) 2009-11-04 CN disclosed