Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | PTGES | O14684 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790765 | 0.94 | NR1I2 (0.66) | NR1I2ESR1L3MBTL1ALOX5PTGES | |
| SCHEMBL5189511 | 0.85 | ESR1 (0.80) | NR1I2ESR1L3MBTL1ALOX5PTGES | |
| Hydrochloric Acid SCHEMBL5795271 | 0.81 | NR1I2 (0.66) | NR1I2ESR1L3MBTL1ALOX5PTGES | |
| SCHEMBL27812675 | 0.80 | NR1I2 (0.64) | NR1I2ESR1L3MBTL1ALOX5PTGES | |
| SCHEMBL10900894 | 0.80 | ALOX5 (0.85) | NR1I2ESR1L3MBTL1ALOX5PTGES | |
| SCHEMBL27716491 | 0.79 | TDP1 (0.61) | NR1I2ESR1L3MBTL1TDP1KEAP1 | |
| SCHEMBL5863768 | 0.78 | ESR1 (0.60) | NR1I2ESR1L3MBTL1CNR2CNR1 | |
| SCHEMBL8466425 | 0.77 | ESR1 (0.76) | NR1I2ESR1L3MBTL1ALOX5PTGES | |
| SCHEMBL11737973 | 0.77 | ESR1 (0.67) | NR1I2ESR1L3MBTL1ALOX5PTGES | |
| SCHEMBL11484294 | 0.77 | ESR1 (0.63) | NR1I2ESR1L3MBTL1ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817767-A | Substituted sulphonamide compound and preparation method, medicine composition and application thereof | SHANGHAI INST BIOL SCIENCES | 2010-09-01 | — | — | CN | disclosed |