Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930242 | 0.77 | BRAF (0.53) | HPGDKDM4EALDH1A1HSD17B10BRAF | |
| SCHEMBL3019904 | 0.77 | BRAF (0.51) | POLBHPGDFABP4ALOX5APFEN1 | |
| SCHEMBL28282536 | 0.76 | KDM4E (0.46) | PARP1POLBHTTHPGDKDM4E | |
| SCHEMBL27813047 | 0.74 | TSHR (0.56) | HTTKDM4EALDH1A1FABP4 | |
| SCHEMBL27791883 | 0.73 | SLC10A2 (0.55) | HPGDKDM4EALDH1A1 | |
| SCHEMBL22638686 | 0.73 | POLB (0.54) | POLBHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16266453 | 0.72 | KDM4E (0.43) | POLBKDM4EALDH1A1HSD17B10FABP4 | |
| SCHEMBL27792180 | 0.72 | KDM4E (0.55) | HTTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL13602442 | 0.72 | HTT (0.49) | POLBHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL27813043 | 0.71 | PTGES2 (0.55) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101808994-A | Be used for Compounds and methods for that kinases regulates with and indication | PLEXXIKON INC | 2010-08-18 | — | — | CN | disclosed |