Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065758 | 0.94 | HTR2C (0.77) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL16457233 | 0.87 | HTR2C (0.72) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL2532290 | 0.87 | HTR2C (0.72) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL22816107 | 0.86 | HTR2C (0.66) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL13197434 | 0.86 | HTR2C (0.66) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL15336102 | 0.86 | HTR2C (0.66) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL13197435 | 0.86 | HTR2C (0.66) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL5668848 | 0.85 | HTR2C (0.70) | HTR2CDRD2HTR2AHTR2B | |
| SCHEMBL31087548 | 0.85 | HTR2C (0.70) | HTR2CDRD2HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL11831649 | 0.84 | HTR2C (0.67) | HTR2CDRD2HTR2AHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646652-A | Quinoline derivatives and pharmaceutical compositions comprising them for selectin inhibition | WYETH CORP US | 2010-02-10 | — | — | CN | disclosed |