Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771699 | 0.82 | NR4A2 (0.37) | NR4A2CYP2D6 | |
| SCHEMBL27792887 | 0.76 | NR4A2 (0.45) | NR4A2MEN1KMT2A | |
| SCHEMBL3165002 | 0.69 | PDCD1 (0.37) | CNR1CNR2CASRMEN1KMT2A | |
| SCHEMBL27909433 | 0.67 | NR4A2 (0.46) | NR4A2MEN1KMT2A | |
| SCHEMBL1759590 | 0.63 | NR4A2 (0.47) | NR4A2MEN1KMT2A | |
| SCHEMBL1760252 | 0.63 | NR4A2 (0.47) | NR4A2MEN1KMT2A | |
| SCHEMBL5592328 | 0.62 | NR4A2 (0.49) | NR4A2MEN1KMT2A | |
| SCHEMBL28046327 | 0.62 | NR4A2 (0.49) | NR4A2 | |
| SCHEMBL3995062 | 0.62 | NR4A2 (0.72) | NR4A2SLC6A4KCNH2 | |
| SCHEMBL27771709 | 0.62 | NR4A2 (0.49) | NR4A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |