Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 11/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856360 | 0.82 | FBP1 (0.68) | FBP1MAPTALDH1A1 | |
| SCHEMBL8856279 | 0.82 | FBP1 (0.68) | FBP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL8856283 | 0.82 | FBP1 (0.68) | FBP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL8856223 | 0.82 | FBP1 (0.68) | FBP1 | |
| SCHEMBL8856356 | 0.82 | FBP1 (0.68) | FBP1MAPTALDH1A1 | |
| SCHEMBL8856230 | 0.82 | FBP1 (0.68) | FBP1 | |
| SCHEMBL2820854 | 0.82 | FBP1 (1.00) | FBP1MEN1KMT2AALDH1A1PRMT1 | |
| SCHEMBL205355 | 0.82 | FBP1 (1.00) | FBP1MEN1KMT2AALDH1A1PRMT1 | |
| SCHEMBL26976895 | 0.82 | FBP1 (0.47) | FBP1ALOX5MEN1LMNAMAPT | |
| SCHEMBL205356 | 0.82 | FBP1 (1.00) | FBP1MEN1KMT2AALDH1A1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101845048-A | Synthetic method of 2-nitro-2,3-dihydrofuran derivative | UNIV ZHEJIANG NORMAL | 2010-09-29 | — | — | CN | disclosed |