Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853767 | 0.78 | EGFR (0.44) | EGFRJAK2ROS1PDGFRAFLT4 | |
| SCHEMBL13942280 | 0.74 | CA12 (0.50) | EGFRJAK2ROS1PDGFRAFLT4 | |
| SCHEMBL15844605 | 0.72 | EGFR (0.50) | EGFRJAK2ROS1PDGFRAFLT4 | |
| SCHEMBL15844661 | 0.72 | EGFR (0.52) | EGFRJAK2ROS1PDGFRAFLT4 | |
| SCHEMBL21751904 | 0.71 | CA12 (0.39) | CA12CA1CA9 | |
| SCHEMBL27847781 | 0.70 | HTR2A (0.37) | — | |
| SCHEMBL27794803 | 0.68 | CA12 (0.52) | EGFRJAK2ROS1PDGFRAFLT4 | |
| SCHEMBL13942278 | 0.68 | TYMP (0.49) | CA12CA1CA2CA9 | |
| SCHEMBL27794804 | 0.68 | CA12 (0.46) | EGFRJAK2ROS1PDGFRAFLT4 | |
| SCHEMBL13941943 | 0.67 | CA12 (0.48) | EGFRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101654465-B | Caobonyl technetium labeled 2-azomycin composition, preparation method and application | UNIV LANGZHOU | 2012-10-03 | — | — | CN | disclosed |
| CN-101654465-A | Caobonyl technetium labeled 2-azomycin composition, preparation method and application | UNIV LANZHOU | 2010-02-24 | — | — | CN | disclosed |