Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751904 | 0.78 | CA12 (0.39) | ALDH1A1S1PR3 | |
| SCHEMBL18530400 | 0.73 | ABCG2 (0.39) | ABCG2TTR | |
| SCHEMBL18530404 | 0.73 | ABCG2 (0.39) | ABCG2TTR | |
| SCHEMBL23921968 | 0.73 | ABCG2 (0.39) | ABCG2TTR | |
| SCHEMBL28452635 | 0.73 | ABCG2 (0.41) | ABCG2SMN1; SMN2ALDH1A1POLBMAPK1 | |
| SCHEMBL19616558 | 0.73 | ABCG2 (0.41) | ABCG2SMN1; SMN2ALDH1A1POLBMAPK1 | |
| SCHEMBL28838991 | 0.71 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL564007 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1POLBMAPK1 | |
| SCHEMBL14915168 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1POLBMAPK1 | |
| SCHEMBL28505243 | 0.68 | KDM4E (0.42) | TTRSMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101921263-A | 2-metridazloe derivative as well as application and preparation method thereof | UNIV LANZHOU | 2010-12-22 | — | — | CN | disclosed |