Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731007 | 0.89 | CYP1A2 (0.43) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL22278960 | 0.83 | CYP1A2 (0.53) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL7865580 | 0.82 | CYP1A2 (0.46) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL29740738 | 0.80 | CYP1A2 (0.59) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL21441714 | 0.79 | CYP1A2 (0.53) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL13756007 | 0.79 | CYP1A2 (0.52) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL7866367 | 0.78 | MEN1 (0.46) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL7858923 | 0.77 | TSHR (0.46) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL20937027 | 0.77 | CYP1A2 (0.50) | CYP1A2TSHRNR1I2PGRADORA3 | |
| SCHEMBL10851453 | 0.77 | APOBEC3A (0.56) | CYP1A2TSHRNR1I2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101665501-B | Method for preparing talipexole | SHANGHAI HAOYUAN BIO PHARMACEUTICAL TECHNOLOGY CO LTD | 2011-04-20 | — | — | CN | disclosed |
| CN-101665501-A | Method for preparing talipexole | SHANGHAI HAOYUAN CHEMEXPRESS B | 2010-03-10 | — | — | CN | disclosed |