SCHEMBL27794869

SCHEMBL27794869

COCCn1cc(C(=O)O)c(=O)c2cc3c(cc21)OCO3

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
KDM4E B2RXH2 3/20 0.72
HPGD P15428 2/20 0.72
HSD17B10 Q99714 2/20 0.72
CYP1A2 P05177 1/20 0.72
CYP2D6 P10635 1/20 0.72
APEX1 P27695 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
TP53 P04637 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
RXFP1 Q9HBX9 5/20 0.48
PDE4A P27815 1/20 0.48
PDE4B Q07343 1/20 0.48
PDE4C Q08493 1/20 0.48
PDE4D Q08499 1/20 0.48
TSHR P16473 2/20 0.47
RAB9A P51151 1/20 0.47
MAPT P10636 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30185626 0.87 ALDH1A1 (0.81) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL11669157 0.85 ALDH1A1 (0.75) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL28034345 0.84 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL29420856 0.84 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL24445 0.84 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL637058 0.84 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL30829037 0.83 KDM4E (0.97) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL27985461 0.83 KDM4E (0.97) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL3467839 0.83 KDM4E (0.97) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Oxolinic Acid SCHEMBL28034329 0.83 KDM4E (0.97) ALDH1A1KDM4EHPGDHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108743525-A A kind of anti-oxidant naproxen injection and preparation method thereof 安徽天安生物科技股份有限公司 2018-11-06 CN claimed
CN-108635393-A A kind of anti-oxidant occrycetin injection and preparation method thereof 安徽天安生物科技股份有限公司 2018-10-12 CN claimed
CN-103728402-B GC method for detecting residual quantity of solvent in compound 北大方正集团有限公司 2017-05-24 CN claimed
CN-103728402-A GC method for detecting residual quantity of solvent in compound UNIV PEKING FOUNDER GROUP CO 2014-04-16 CN claimed
CN-107445977-B A kind of water solubility Marbofloxacin and the preparation method and application thereof 江西傲新生物科技有限公司 2019-08-09 CN disclosed
CN-108743525-A A kind of anti-oxidant naproxen injection and preparation method thereof 安徽天安生物科技股份有限公司 2018-11-06 CN disclosed
CN-108743525-A A kind of anti-oxidant naproxen injection and preparation method thereof 安徽天安生物科技股份有限公司 2018-11-06 CN disclosed
CN-108635393-A A kind of anti-oxidant occrycetin injection and preparation method thereof 安徽天安生物科技股份有限公司 2018-10-12 CN disclosed
CN-108635393-A A kind of anti-oxidant occrycetin injection and preparation method thereof 安徽天安生物科技股份有限公司 2018-10-12 CN disclosed
CN-107445977-A A kind of water-soluble Marbofloxacin and preparation method and application 江西傲新生物科技有限公司 2017-12-08 CN disclosed
CN-103728402-B GC method for detecting residual quantity of solvent in compound 北大方正集团有限公司 2017-05-24 CN disclosed
CN-103323594-B A kind of enzyme linked immunological kit and application thereof detecting QNS in aquatic products Beijing Kwinbon Biotechnology Co.,Ltd. (CN) 2016-03-30 CN disclosed
CN-103018453-B A kind of chemical luminescence ELISA detection kit of QNS Beijing Kwinbon Biotechnology Co.,Ltd. (CN) 2015-08-12 CN disclosed
CN-103728402-A GC method for detecting residual quantity of solvent in compound UNIV PEKING FOUNDER GROUP CO 2014-04-16 CN disclosed
CN-103323594-A Enzyme-linked immunoassay kit for detecting quinolone drugs in aquatic products and its application BEIJING KWINBON BIOTECH CO LTD 2013-09-25 CN disclosed
CN-103018453-A Quinolone drug chemiluminescence enzyme-linked immunodetection kit BEIJING KWINBON BIOTECH CO LTD 2013-04-03 CN disclosed
CN-101672792-B Detection method of quinolone drugs, detection reagent kit and application GUANGDONG INST FOR DRUG CONTROL 2012-01-11 CN disclosed
CN-101672792-A Detection method of quinolone drugs, detection reagent kit and application GUANGDONG INST FOR DRUG CONTRO 2010-03-17 CN disclosed
CN-101672781-A Application of ferric ammonium sulfate for detecting quinolone drugs GUANGDONG INST FOR DRUG CONTRO 2010-03-17 CN disclosed