SCHEMBL27794876

SCHEMBL27794876

Nc1ccc(-c2ccc(N)c(S(=O)(=O)O)c2N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
TSHR P16473 5/20 0.44
NT5E P21589 2/20 0.44
CYP3A4 P08684 4/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 2/20 0.38
CASP1 P29466 2/20 0.38
RECQL P46063 2/20 0.38
ALOX15 P16050 2/20 0.38
THRB P10828 1/20 0.38
TDP1 Q9NUW8 4/20 0.38
TP53 P04637 2/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
CASP7 P55210 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA1 P00915 5/20 0.37
CA2 P00918 5/20 0.37
CA12 O43570 4/20 0.37
CA9 Q16790 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28351799 0.88 ALDH1A1 (0.47) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL29566314 0.87 ALDH1A1 (0.45) ALDH1A1TSHRNT5ECYP3A4HSD17B10
SCHEMBL1270822 0.87 ALDH1A1 (0.45) ALDH1A1TSHRNT5ECYP3A4HSD17B10
SCHEMBL27420816 0.86 DAPK1 (0.41) ALDH1A1TSHRHSD17B10SMN1; SMN2DAPK1
Sulfuric Acid SCHEMBL22406115 0.79 ALDH1A1 (0.42) ALDH1A1TSHRNT5ECYP3A4HSD17B10
SCHEMBL27487602 0.77 ALDH1A1 (0.42) ALDH1A1TSHRNT5ECYP3A4HSD17B10
SCHEMBL5181911 0.76 ALDH1A1 (0.41) ALDH1A1TSHRNT5ECYP3A4HSD17B10
SCHEMBL28370213 0.76 ALDH1A1 (0.49) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL30297625 0.76 ALDH1A1 (0.38) ALDH1A1TSHRNT5ECYP3A4HSD17B10
SCHEMBL28348479 0.74 ALDH1A1 (0.47) ALDH1A1TSHRNT5EHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101674881-B Metal salt nanogel-containing polymers BAYER INNOVATION GMBH 2013-02-06 CN disclosed
CN-101674881-A The polymer that contains metal salt nanogel GUENTER HELLING 2010-03-17 CN disclosed