2-Chlorophenol

2-Chlorophenol

SCHEMBL27794877

CC#N.Oc1ccccc1Cl

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
TSHR P16473 6/20 0.46
HSD17B10 Q99714 4/20 0.41
CA2 P00918 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
LMNA P02545 2/20 0.41
CYP3A4 P08684 2/20 0.41
KDM4E B2RXH2 2/20 0.41
EGFR P00533 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41
NFKB1 P19838 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
CA12 O43570 1/20 0.41
GMNN O75496 1/20 0.41
FYN P06241 1/20 0.41
POLB P06746 1/20 0.41
CA3 P07451 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Chlorophenol SCHEMBL8579722 0.87
2-Chlorophenol SCHEMBL30051129 0.87
2-Chlorophenol SCHEMBL28788416 0.85 ALDH1A1 (0.88) ALDH1A1TSHRHSD17B10CA2TDP1
2-Chlorophenol SCHEMBL28088500 0.85 ALDH1A1 (0.88) ALDH1A1TSHRHSD17B10CA2TDP1
1,2-Dichlorobenzene SCHEMBL27555218 0.85 ALDH1A1 (0.88) ALDH1A1TSHRHSD17B10CA2TDP1
2-Chlorophenol SCHEMBL8961529 0.84 ALDH1A1 (1.00) ALDH1A1TSHRHSD17B10CA2TDP1
2-Chlorophenol SCHEMBL29354452 0.84
2-Chlorophenol SCHEMBL12279 0.84
2-Chlorophenol SCHEMBL31689352 0.82 ALDH1A1 (0.83) ALDH1A1TSHRHSD17B10CA2TDP1
2-Chlorophenol SCHEMBL7865189 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912439-B Method for continuously and rapidly preparing DL-phenylglycine and analogue thereof by using cyanohydrin method 天宝动物营养科技股份有限公司 2022-09-23 CN disclosed
CN-109824531-B Method for continuously and rapidly preparing DL-phenylglycine and analogues thereof 天宝动物营养科技股份有限公司 2022-08-23 CN disclosed
CN-109912439-A Method for continuously and rapidly preparing DL-phenylglycine and analogue thereof by using cyanohydrin method 禄丰天宝磷化工有限公司 2019-06-21 CN disclosed
CN-109824531-A Method for continuously and rapidly preparing DL-phenylglycine and analogues thereof 禄丰天宝磷化工有限公司 2019-05-31 CN disclosed
CN-101674844-A tetrazolyl macrocyclic hepatitis c serine protease inhibitors ENANTA PHARM INC 2010-03-17 CN disclosed