Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 8/20 | 0.42 |
| ▸ | ACE | P12821 | 8/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.42 |
| ▸ | CPA1 | P15085 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778117 | 1.00 | PPARG (0.42) | PPARGPPARAMMEACEACE2 | |
| Hydrochloric Acid SCHEMBL6770872 | 0.98 | PPARG (0.41) | PPARGPPARAMMEACEACE2 | |
| SCHEMBL2778931 | 0.89 | POLB (0.52) | MMEACEACE2CPA1POLB | |
| SCHEMBL2778934 | 0.89 | POLB (0.52) | MMEACEACE2CPA1POLB | |
| SCHEMBL2779693 | 0.81 | ACE (0.46) | PPARGPPARAMMEACEACE2 | |
| SCHEMBL2779696 | 0.81 | ACE (0.46) | PPARGPPARAMMEACEACE2 | |
| SCHEMBL28565794 | 0.80 | MME (0.57) | MMEACEACE2CPA1 | |
| SCHEMBL8525049 | 0.80 | FOLH1 (0.49) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL8027755 | 0.80 | FOLH1 (0.49) | MMEACEACE2CPA1FOLH1 | |
| Hydrochloric Acid SCHEMBL6775146 | 0.79 | ACE (0.44) | PPARGPPARAMMEACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248901-A1 | Streptogramines and method for preparing same by mutasynthesis | Aventis Pharma S.A. (FR) | 2010-11-10 | — | — | EP | disclosed |
| EP-0770132-B1 | NEW STREPTOGRAMINES | AVENTIS PHARMA SA (FR) | 2010-09-08 | — | — | EP | disclosed |
| CN-1152338-A | Streptogramines and method for preparing same by mutasynthesis | RHONE POULENC RORER SA (FR) | 1997-06-18 | — | — | CN | disclosed |
| EP-0770132-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | Aventis Pharma S.A. (FR) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001901-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | RHONE-POULENC RORER S.A. (FR) | 1996-01-25 | — | — | WO | disclosed |