Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.46 |
| ▸ | MME | P08473 | 9/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.46 |
| ▸ | CPA1 | P15085 | 8/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779693 | 1.00 | ACE (0.46) | ACEMMEACE2CPA1FOLH1 | |
| Hydrochloric Acid SCHEMBL6775146 | 0.98 | ACE (0.44) | ACEMMEACE2CPA1FOLH1 | |
| SCHEMBL2780446 | 0.86 | LMNA (0.54) | ACEMMEACE2CPA1ALDH1A1 | |
| SCHEMBL2780445 | 0.86 | LMNA (0.54) | ACEMMEACE2CPA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6774734 | 0.83 | MME (0.47) | ACEMMEACE2CPA1FOLH1 | |
| SCHEMBL22444653 | 0.81 | PPARG (0.47) | ACEMMEACE2CPA1FOLH1 | |
| SCHEMBL26008168 | 0.81 | PPARG (0.47) | ACEMMEACE2CPA1FOLH1 | |
| SCHEMBL2779520 | 0.81 | PPARG (0.42) | ACEMMEACE2CPA1FOLH1 | |
| SCHEMBL2778117 | 0.81 | PPARG (0.42) | ACEMMEACE2CPA1FOLH1 | |
| Hydrochloric Acid SCHEMBL6770872 | 0.80 | PPARG (0.41) | ACEMMEACE2CPA1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248901-A1 | Streptogramines and method for preparing same by mutasynthesis | Aventis Pharma S.A. (FR) | 2010-11-10 | — | — | EP | disclosed |
| EP-0770132-B1 | NEW STREPTOGRAMINES | AVENTIS PHARMA SA (FR) | 2010-09-08 | — | — | EP | disclosed |