Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370745 | 0.83 | CHRM2 (0.58) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL25610774 | 0.82 | CHRM2 (0.58) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL27969478 | 0.82 | CHRM2 (0.58) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL25434590 | 0.80 | CHRM2 (0.41) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL2762931 | 0.77 | CHRM2 (0.56) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL2933098 | 0.77 | CHRM2 (0.66) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL12441787 | 0.77 | CHRM2 (0.66) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL11161473 | 0.75 | KEAP1 (0.57) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL6704158 | 0.75 | CHRM2 (0.60) | CHRM2CHRM1KCNH2CYP2D6CHRM3 | |
| SCHEMBL1847210 | 0.75 | CHRM2 (0.60) | CHRM2CHRM1KCNH2CYP2D6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663263-A | Solid forms comprising (-) -O-desmethylvenlafaxine and uses thereof | SEPRACOR INC | 2010-03-03 | — | — | CN | disclosed |