Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 11/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326299 | 0.93 | FGFR4 (0.39) | FGFR4FABP4HTR6CYP3A4CHRM1 | |
| Tert-Butyl Formate SCHEMBL27774812 | 0.88 | HTR6 (0.38) | FABP4HTR6CYP3A4CHRM1POLB | |
| Tert-Butyl Formate SCHEMBL27774753 | 0.84 | HTR6 (0.42) | FGFR4HTR6CYP3A4POLBL3MBTL1 | |
| Tert-Butyl Formate SCHEMBL27774772 | 0.84 | HTR6 (0.49) | HTR6CYP3A4POLBL3MBTL1 | |
| Tert-Butyl Formate SCHEMBL27795740 | 0.81 | HTR6 (0.41) | FABP4HTR6POLBL3MBTL1 | |
| Tert-Butyl Formate SCHEMBL27774743 | 0.81 | HTR6 (0.50) | HTR6CYP3A4POLBL3MBTL1RORC | |
| SCHEMBL3325153 | 0.80 | HTR6 (0.43) | FABP4HTR6CYP3A4CHRM1 | |
| SCHEMBL3327322 | 0.80 | HTR6 (0.39) | FABP4HTR6CYP3A4CHRM1POLB | |
| Hydrochloric Acid SCHEMBL3327844 | 0.79 | HTR6 (0.42) | FABP4HTR6CYP3A4CHRM1 | |
| SCHEMBL3327854 | 0.79 | HTR6 (0.42) | FGFR4FABP4HTR6CHRM1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679381-A | Azetidin compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor | ABBOTT GMBH & CO KG | 2010-03-24 | — | — | CN | claimed |
| CN-101679381-A | Azetidin compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor | ABBOTT GMBH & CO KG | 2010-03-24 | — | — | CN | disclosed |