Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.56 |
| ▸ | GCG | P01275 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796159 | 1.00 | GRN (0.56) | GRNSORT1GCGNTSR1KDR | |
| SCHEMBL2822278 | 0.85 | RAB9A (0.53) | GCGKDRRAB9ANPC1KDM4E | |
| SCHEMBL27796158 | 0.83 | SCN9A (0.53) | NTSR1KDRRAB9ANPC1KDM4E | |
| SCHEMBL27796161 | 0.83 | SCN9A (0.53) | NTSR1KDRRAB9ANPC1KDM4E | |
| SCHEMBL781092 | 0.82 | KDM4E (0.59) | GCGKDRRAB9ANPC1KDM4E | |
| SCHEMBL9057065 | 0.82 | KDM4E (0.59) | GCGKDRRAB9ANPC1KDM4E | |
| SCHEMBL29516918 | 0.82 | KDM4E (0.59) | GCGKDRRAB9ANPC1KDM4E | |
| SCHEMBL661286 | 0.82 | KDM4E (0.59) | GCGKDRRAB9ANPC1KDM4E | |
| SCHEMBL15643459 | 0.79 | GCG (0.45) | GCGNTSR1KDRRAB9AKDM4E | |
| SCHEMBL15643457 | 0.79 | GCG (0.45) | GCGNTSR1KDRRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101885653-B | Synthesis method of N-heteroaryl amino acid | UNIV CHENGDU TECHNOLOGY | 2013-07-31 | — | — | CN | disclosed |
| CN-101885653-A | Synthesis method of N-heteroaryl amino acid | UNIV CHENGDU TECHNOLOGY | 2010-11-17 | — | — | CN | disclosed |