Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30482807 | 1.00 | GSK3A (0.39) | GSK3AGSK3BS100A4CDC25BTDP1 | |
| SCHEMBL13859949 | 0.85 | TSHR (0.35) | S100A4CDC25BTDP1CYP19A1TNF | |
| SCHEMBL17936813 | 0.76 | — | — | |
| SCHEMBL2589448 | 0.76 | — | — | |
| SCHEMBL401773 | 0.74 | TRPA1 (0.40) | CYP19A1CYP1A2CA12CA1CA2 | |
| SCHEMBL28513579 | 0.73 | GSK3A (0.40) | GSK3AGSK3BCYP19A1TNF | |
| SCHEMBL13859947 | 0.73 | CA12 (0.33) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL4964849 | 0.71 | TRPA1 (0.32) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL9276484 | 0.70 | — | — | |
| SCHEMBL13859957 | 0.69 | CYP11B1 (0.34) | CYP19A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507948-A | Method for producing nitrogenated heterocyclic N-oxide compound | NISSAN CHEMICAL IND LTD | 2015-04-08 | — | — | CN | claimed |
| JP-2008514565-A | — | — | 2008-05-08 | — | — | JP | claimed |
| EP-1793822-A1 | TRICYCLES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. Hoffmann-Roche AG (CH) | 2007-06-13 | — | — | EP | claimed |
| WO-2006032519-A1 | TRICYCLES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-30 | — | — | WO | claimed |
| WO-2003103666-A2 | NOVEL 4,5-DIHYDRO-IMIDAZO[4,5,1-IJ]QUINOLIN-6-ONES | ALTANA PHARMA AG (DE) | 2003-12-18 | — | — | WO | claimed |
| WO-2003104233-A1 | 4,5-DIHYDRO-IMIDAZO (4,5,1-IJ) QUINOLIN-6-ONES DERIVATIVES AND THEIR USE AS POLY (ADP-RIBOSYL) TRANSFERASE (PARP) INHIBITORS | ALTANA PHARMA AG (DE) | 2003-12-18 | — | — | WO | claimed |
| WO-2003020698-A2 | PROTEIN TYROSINE KINASE INHIBITORS | PROCHON BIOTECH LTD. (IL) | 2003-03-13 | — | — | WO | claimed |
| CN-119317623-A | Tricyclic quinolone BCL6 bifunctional degradation agents | 树线生物科学公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-113614082-B | Material for organic electroluminescent device | 默克专利有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117362368-A | Macrolide-quinolone derivative and preparation method and application thereof | 北京理工大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| EP-3961640-A1 | CONTROL SYSTEM FOR CONTROL OF DISTRIBUTION OF MEDICATION | Zogenix International Limited (GB) | 2022-03-02 | — | — | EP | disclosed |
| EP-3947372-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2022-02-09 | — | — | EP | disclosed |
| CN-87104651-A | The BCD tricyclic ergoline part-structure analoguse | — | 1988-01-13 | — | — | CN | disclosed |
| EP-0015308-B1 | PROCESS FOR THE SELECTIVE DEGRADATION OF SIDE CHAINS OF STEROID COMPOUNDS AND FOR THE PREPARATION OF THE APPROPRIATE DEFECTIVE MICROORGANISM MUTANTS AND MICROORGANISM STRAINS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-04-29 | — | — | EP | disclosed |
| EP-0061688-B1 | PROCESS FOR THE CONTROLLED MICROBIAL DEGRADATION OF BILE ACIDS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4362815-A | DEGRADATION OF STEROIDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-12-07 | — | — | US | disclosed |
| EP-0061688-A1 | Process for the controlled microbial degradation of bile acids | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-10-06 | — | — | EP | disclosed |
| EP-0015308-A1 | Process for the selective degradation of side chains of steroid compounds and for the preparation of the appropriate defective microorganism mutants and microorganism strains | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-09-17 | — | — | EP | disclosed |
| EP-0005505-A2 | Open-cell foamed polyurethane resins containing compounds forming chelates and/or complexes of chelates, process for their preparation and their application to the adsorption of heavy-metal ions from waste water | BASF Aktiengesellschaft (DE) | 1979-11-28 | — | — | EP | disclosed |