Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749123 | 0.98 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL2843842 | 0.81 | TOP2A (0.51) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL5241436 | 0.80 | TSHR (0.54) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL4520816 | 0.80 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL28864069 | 0.79 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL2399636 | 0.77 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL28141587 | 0.77 | DPP4 (0.42) | MKNK1ALDH1A1PDPK1CDK2HSD17B10 | |
| SCHEMBL28243803 | 0.77 | BRD4 (0.49) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL9621210 | 0.76 | PI4KA (0.81) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL30484606 | 0.76 | TSHR (0.50) | PI4KAPI4K2BPI4K2API4KBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679432-A | Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors | SIGNAL PHARM LLC | 2010-03-24 | — | — | CN | claimed |